What can acyclovir cause while being pregnant?
Acyclovir, an antiviral nucleoside analogue, is a widely used agent highly specific for herpes simplex and varicella-zoster viruses. Unintended exposure to acyclovir early in pregnancy, which is not uncommon, may cause excessive maternal and physician anxiety.
Does acyclovir cause birth defects?
This study also included dermatological acyclovir exposure in early pregnancy (n = 474) and found no association with birth defects. A study using prescription data and questionnaire information on pregnancy outcomes found no birth defects in 22 pregnancies exposed to acyclovir or famciclovir.
What category is acyclovir for pregnancy?
All formulations of acyclovir are assigned FDA pregnancy category C status ****, which indicates that safety in human pregnancies has not been determined; therefore, the drug should not be used during pregnancy unless the potential benefit justifies the potential risk to the fetus.
Taking antiviral medications can prevent serious flu complications, such as pneumonia. Although it’s important to be cautious with any medication during pregnancy, research suggests that the benefits outweigh the potential risks of antiviral medications to treat flu during pregnancy.
What are the contraindications of acyclovir?
The only absolute contraindication to acyclovir is hypersensitivity. Cautions include renal failure/impairment, immunocompromised host, potential risk of thrombotic thrombocytopenic purpura (TTP), and hemolytic uremic syndrome (HUS)).
What is category B in pregnancy?
Category B drugs include prenatal vitamins, acetaminophen and several other medications used routinely and safely during pregnancy. If there is a clinical need for a Category B drug, it is considered safe to use it.